Passive patches, which release the active substance via passive diffusion, are limited to relatively small-molecule and lipophilic active substances, since only these can penetrate the skin in therapeutically relevant amounts. As a result, active substances with larger molecules, such as peptides, proteins and vaccines, cannot be administered this way. But these new, often biotechnologically produced, drugs frequently have major potential for the therapy of diseases that until now have been inadequately treated – primarily cancer.
Pain-free injections with LTS microneedles
LTS Microneedles that are long enough to penetrate the outer layer of skin but too short to irritate nerves and blood vessels. They can be used to inject active substances with larger molecules into the skin, an application that is largely pain-free. Microneedles create tiny holes in the outermost layer of skin, which significantly increases the rate at which the active substance is absorbed.
LTS is currently researching a number of different microneedles made from different materials and with different gauges, designs and sizes for a wide range of applications.